Singularis Superior Diosmin Complex 60 capsules

The dietary supplement Singularis Superior Diosmin Complex is a combination of high-quality active nutrients. It contains diosmin, hesperidin, vitamin C, and extracts of Ruscus spinosus rhizome and black pepper. The product is presented in the form of vegetable capsules, making it suitable for vegans and vegetarians.

The diosmin and hesperidin have been the subject of numerous scientific studies demonstrating their beneficial effects on the cardiovascular system (notably on the condition of the veins in the lower limbs). Among the active substances used in the prevention of chronic venous disease, the purified flavonoid fraction of diosmin and hesperidin remains the most recommended agent[3]. [3]

The aforementioned flavonoids also promote blood sugar control, lipid profiles, kidney function, liver enzymes, and antioxidant enzymes, and modulate signaling pathways related to glucose absorption and insulin sensitivity, which are involved in the pathogenesis of diabetes and its complications.

Thanks to the addition of vitamin C and black pepper extract, the Singularis product exhibits antioxidant activity [ID 2115]. It thus supports the body in combating oxidative stress, which causes cellular dysfunction and leads to earlier cell death.

Furthermore, the black pepper extract supports the digestive system and is beneficial for the liver [ID 2113]. It also promotes the functioning of the nervous system [ID 2111] and maintains normal functions of the female reproductive system.

Ascorbic acid also participates in collagen synthesis [ID 130]. Collagen is a protein that constitutes the main structural element of connective tissue, found notably in blood vessels, and is responsible for maintaining their elasticity.

In summary, Singularis Superior Diosmin Complex is a high-quality dietary supplement containing substances such as diosmin, hesperidin, bioperine, and vitamin C. The Singularis product stands out for its simple and natural composition. Thanks to the exclusive use of plant-based ingredients, it is suitable for vegans and vegetarians.

1 Gandhi GR, Vasconcelos ABS, Wu DT, Li HB, Antony PJ, Li H, Geng F, Gurgel RQ, Narain N, Gan RY. Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies. Nutrients. 2020 Sep 23;12(10):2907. doi: 10.3390/nu12102907. PMID: 32977511; PMCID: PMC7598193.

2 Karetová D, Suchopár J, Bultas J. Diosmin/hesperidin: a cooperating tandem, or is diosmin crucial and hesperidin an inactive ingredient only? Vnitr Lek. 2020 Spring;66(2):97-103. English. PMID: 32942884.

3 Gavorník P, Dukát A, Gašpar Ľ, Gavorníková E. Present and future in the management of venous vascular diseases [Présent et futur dans la prise en charge des maladies vasculaires veineuses]. Vnitr Lek. 2015 Feb;61(2):151-6. Czech. PMID: 25813260.

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